Ohayocon

National Harbor, MD

January 29 - 31, 2010

http://www.ohayocon.org/

 Katsucon

National Harbor, MD

February 12 -14, 2010

http://www.katsucon.com/

  Naka-kon

Kansas City, MO

February 19 - 21, 2010

http://naka-kon.com/

Megacon

Orlando, FL

March 12 - 14, 2010

http://www.megaconvention.com/ 

 Sakuracon

Seattle, WA

April 2 - 4, 2010

http://www.sakuracon.org/

 Anime Boston

Boston, MA

April 2 - 4, 2010

 Anime Central

Rosemont, IL

May 14 - 16, 2010

http://www.acen.org

 Animazement

Durham, NC

May 28 - 30, 2010

http://www.animazement.org/

 Anime Mid Atlantic

Chesapeake, VA

June 18 - 20, 2010

http://www.animemidatlantic.com/

 Anime Expo

Los Angeles, CA

July 1 - 4, 2010

http://www.anime-expo.org/

 Connecticon

Hartford, CT

July 9 - 11, 2010

http://www.connecticon.org/forums/

 Otakon

Baltimore, MD

July 30 - August 1, 2010

http://www.otakon.com/

 Anime Weekend Atlanta

Atlanta, GA

September 17 - 19, 2010

http://www.awa-con.com/

 Anime USA

Arlington, VA

Date - To be announced

http://www.animeusa.org/

 NekoCon

Hampton, VA

November 5 - 7, 2010

http://www.nekocon.com/